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Lexicon Pharmaceuticals, Inc.

Pipeline3 assets

  • SotagliflozinINPEFA / ZYNQUISTA / SGLT1 / SGLT2 / Small Molecule / Cardiometabolic
    Heart FailureApprovedactiveUnited StatesHypertrophic Cardiomyopathy (HCM)Phase 3activeGlobalType 1 Diabetes (T1D)RegistrationactiveUnited States
  • PilavapadinLX9211 / AAK1 / Small Molecule / Pain / Neurology
    Diabetic Peripheral Neuropathic Pain (DPNP)Phase 2bactiveUnited StatesPostherpetic Neuralgia (PHN)Phase 2inactiveUnited States
  • LX9851LX9851 / ACSL5 / Small Molecule / Metabolism
    Obesity / Weight ManagementPhase 1activeGlobal

Latest news15 items

All news

Lexicon to Present Data at the American Academy of Neurology (AAN) Annual Meeting

Oral presentation highlights additional data from PROGRESS Phase 2b study of pilavapadin supporting selection of 10mg as optimal dose for Phase 3 development in DPNP New data on spasticity further validates the broader potential importance of the AAK1 pathway in neurologic diseases THE WOODLANDS,

Presentation / Abstract • Phase 2

Lexicon to Present Data on Effect of Kidney Function on the Long-term Efficacy and Safety of Sotagliflozin in Patients with Type 1 Diabetes at 19th International Conference on Advanced Technologies & Treatments for Diabetes

Post hoc data analysis concluded that sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, improved glycemic control after one year in patients with normal and mildly reduced kidney function THE WOODLANDS, Texas, March 11, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc.

Presentation / Abstract

Lexicon Announces Proposed Public Offering of Common Stock

THE WOODLANDS, Texas, Jan. 29, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) (“ Lexicon ”) today announced that it has commenced an underwritten public offering to offer and sell, subject to market and other conditions, shares of its common stock, par value $0.001.

Lexicon Pharmaceuticals, Inc. • Endpoint Arena