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Gilead Sciences, Inc.

Pipeline19 assets

  • LenacapavirHIV capsid inhibitor / Long-acting injectable / Virology
    HIV Prevention (PrEP, PURPOSE 365)Phase 3HIV Treatment (in combinations)Phase 3HIV Treatment (with bNAbs)Phase 2
  • Bictegravir/lenacapavir oral combinationINSTI + capsid inhibitor / Oral / Virology
    HIV Treatment (virologically suppressed, ARTISTRY-1 & ARTISTRY-2)Phase 3
  • Islatravir/lenacapavir oral combinationLong-acting oral / Virology
    HIV Treatment (virologically suppressed, ISLEND-1 & ISLEND-2)Phase 3
  • Lenacapavir + teropavimab + zinlirvimabCapsid + bNAbs / Long-acting injectable / Virology
    HIV Treatment (virologically suppressed)Phase 2
  • GS-1720/GS-4182GS-1720/GS-4182 / INSTI/capsid inhibitor / Long-acting oral / Virology
    HIV Treatment (WONDERS-1 & -2)Phase 2
  • Teropavimab + zinlirvimabbNAbs / Broadly neutralizing antibodies / Virology
    HIV CurePhase 2
  • VesatolimodVirology
    HIV Cure (FRESH)Phase 2
  • HBV CurePhase 2
  • HepcludexHepcludex / Virology
    Chronic HDV with compensated liver disease (MYR301)FiledBLA pending (US); Approved (EU)USEU
  • EdecesertibInflammation
    Lupus (COSMIC)Phase 2
  • Inflammatory bowel disease (PALEKONA)Phase 2
  • α4β7 inhibitorα4β7 / Inflammation
    Inflammatory Bowel Disease (SWIFT)Phase 2
  • Sacituzumab govitecan-hziyAntibody-drug conjugate / Oncology
    1L metastatic triple-negative breast cancer (PD-L1-, ASCENT-03)FiledsBLA pendingUS1L metastatic triple-negative breast cancer (PD-L1+, with pembrolizumab, ASCENT-04)FiledsBLA pendingUSHigh risk adjuvant triple-negative breast cancer (with pembrolizumab, ASCENT-05)Phase 3
  • Axicabtagene ciloleucelCD19 CAR / Cell therapy / Oncology
    2L+ high-risk follicular lymphoma (ZUMA-22)Phase 31L high-risk large B-cell lymphoma (ZUMA-23)Phase 3
  • Brexucabtagene autoleucelCD19 CAR / Cell therapy / Oncology
    Pediatric acute lymphocytic leukemia/non-Hodgkin lymphoma (ZUMA-4)Phase 2
  • Anitocabtagene autoleucelCell therapy / Oncology
    2-4L relapsed/refractory multiple myeloma (iMMagine-3)Phase 34L+ relapsed/refractory multiple myeloma (iMMagine-1)FiledBLA pendingUS
  • KITE-363KITE-363 / CD19/CD20 bicistronic / Cell therapy / Oncology
    Relapsed/refractory diffuse large B-cell lymphomaPhase 1RMAT designationRheumatology (autoimmune)Phase 1
  • DenikitugGS-1811 / Oncology
    Advanced cancersPhase 1
  • Domvanalimab + zimberelimabAnti-TIGIT + anti-PD1 / Combination therapy / Oncology
    1L metastatic non-small cell lung cancer (with chemo, STAR-121)Phase 31L head and neck squamous cell carcinoma (VELOCITY-HNSCC)Phase 2

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Gilead Sciences, Inc. • Endpoint Arena