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CytomX Therapeutics, Inc.

Pipeline3 assets

  • varsetatug masetecanCX-2051 / Varseta-M / EpCAM / Probody ADC; Topo-1 payload / Oncology
    3L+ metastatic colorectal cancerPhase 1active2L/3L mCRC; Varseta-M + bevacizumabtrials anticipated 2H 20262L mCRC; Varseta-M + bevacizumab + chemotherapytrials anticipated 2H 2026
  • CX-801CX-801 / IFN-alpha 2b / Probody cytokine / Oncology
    Advanced/metastatic melanomaPhase 1active
  • CX-908CX-908 / P-Cadherin x CD3 / Probody T-cell engager / Oncology
    Solid tumorsPreclinicalactive

Latest news11 items

All news

CytomX Therapeutics to Present at Upcoming June Investor Conferences

SOUTH SAN FRANCISCO, Calif., May 21, 2026 (GLOBE NEWSWIRE) -- CytomX Therapeutics, Inc. (Nasdaq: CTMX), a leader in the field of masked, conditionally activated biologics, today announced that management will participate in the following investor conferences in June.

CytomX Therapeutics Announces 2025 Financial Results and Provides Business Update

- Announced Positive Data from Phase 1 Dose Expansion Study of varsetatug masetecan (“Varseta-M”) EpCAM PROBODY ® ADC in Patients with Advanced Colorectal Cancer (CRC) - - FDA interactions targeted for mid-year with goal to align on potential Varseta-M registrational trial design in late line CRC -

Trial Results • Phase 1

CytomX’s Varsetatug Masetecan (EpCAM PROBODY® ADC) Continues to Demonstrate Positive Data Supporting Potential as a New Treatment Option in Late-Line Colorectal Cancer

- Confirmed response rates in expansion cohorts of 32% at 10 mg/kg Q3W dose and 20% at 8.6 mg/kg Q3W - - Estimated progression free survival of 7.1 months at 10 mg/kg and 6.8 months at 8.6 mg/kg - - Grade 3 diarrhea rate of 10% in ongoing dose optimization cohorts - - FDA interactions targeted for

Trial Results • Phase 1

CytomX Therapeutics to Present at Upcoming February Conferences

SOUTH SAN FRANCISCO, Calif., Feb. 04, 2026 (GLOBE NEWSWIRE) -- CytomX Therapeutics, Inc. (Nasdaq: CTMX), a leader in the field of masked, conditionally activated biologics, today announced that management will participate in the following conferences in February.

CytomX Therapeutics, Inc. • Endpoint Arena