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Astellas Pharma Inc.

Pipeline18 assets

  • zolbetuximabIMAB362 / VYLOY / Claudin 18.2 / Antibody / Oncology
    Gastric and gastroesophageal junction adenocarcinoma, combo with pembrolizumab and chemotherapyFiledEuropeJapan
  • gilteritinibASP2215 / XOSPATA / FLT3 / Small molecule / Oncology
    Newly diagnosed acute myeloid leukemia with high intensity induction chemotherapyPhase 3Post-chemotherapy maintenance acute myeloid leukemiaPhase 3Post-hematopoietic stem cell transplant maintenance acute myeloid leukemiaPhase 3
  • enfortumab vedotinASG-22ME / PADCEV / Nectin-4 / Antibody-drug conjugate (ADC) / Oncology
    Cisplatin-eligible muscle-invasive bladder cancer, combo with pembrolizumabFiledEuropeUSCisplatin-ineligible muscle-invasive bladder cancer, combo with pembrolizumabFiledEuropeJapanBladder-sparing muscle-invasive bladder cancer, combo with pembrolizumabPhase 2
  • fezolinetantESN364 / VEOZAH / NK3 receptor / Small molecule / Women's Health
    Vasomotor symptoms due to menopausePhase 3ChinaVasomotor symptoms in breast cancer patients on adjuvant endocrine therapyPhase 2
  • zocaglusagene nuzaparvovecAT845 / GAA gene replacement / Gene therapy (AAV-based gene therapy) / Genetic Regulation
    Pompe diseasePhase 1
  • ASP2957ASP2957 / MTM1 gene replacement / Gene therapy (AAV-based gene therapy) / Genetic Regulation
    X-linked myotubular myopathyPhase 1
  • setidegrasibKRAS G12D / Small molecule degrader / Targeted Protein Degradation
    Pancreatic ductal adenocarcinomaPhase 3
  • ASP7317ASP7317 / Retinal pigment epithelial cells / Cell therapy / Ophthalmology
    Geographic atrophy secondary to age-related macular degenerationPhase 1
  • ASP1002ASP1002 / Claudin 4/CD137 / T-cell engager bispecific antibody / Oncology
    Gastric and gastroesophageal junction adenocarcinoma; pancreatic adenocarcinomaPhase 1
  • ASP5834ASP5834 / Pan-KRAS / Small molecule degrader / Oncology
    CancerPhase 1
  • VIR-5500VIR-5500 / PSMA/CD3 / T-cell engager / Oncology
    Prostate cancerPhase 1
  • ASP2998ASP2998 / TROP2 / Antibody-drug conjugate (ADC) / Oncology
    CancerPhase 1
  • ASP2138ASP2138 / Claudin 18.2/CD3 / T-cell engager bispecific antibody / Oncology
    CancerPhase 2
  • ASP546CASP546C / Claudin 18.2 / Antibody-drug conjugate (ADC) / Oncology
    CancerPhase 2Europe
  • abiraterone decanoateASP5541/PRL-02 / CYP17 lyase / Small molecule / Oncology
    Prostate cancerPhase 2
  • mirabegronYM178 / Beta-3 receptor / Small molecule / Urology
    Neurogenic detrusor overactivity in pediatric patients aged 6 months to less than 3 yearsPhase 3Europe
  • roxadustatASP1517/FG-4592 / HIF-PH / Small molecule / Nephrology
    Anemia associated with chronic kidney disease in pediatric patientsPhase 3Europe
  • pudexacianinium chlorideASP5354 / Drug-device combination / Other
    Intraoperative ureter visualization for minimally invasive and open abdominopelvic surgeriesPhase 3

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Astellas Pharma Inc. • Endpoint Arena