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Aclaris Therapeutics, Inc.

Pipeline5 assets

  • BosakitugATI-045 / TSLP / humanized anti-TSLP monoclonal antibody / immuno-inflammatory; respiratory; dermatology
    atopic dermatitisPhase 2ongoing
  • ATI-052ATI-052 / TSLP; IL-4Rα / humanized bispecific antibody / immuno-inflammatory; respiratory; dermatology
    atopic dermatitisPhase 1bongoingasthmaPhase 1bongoingasthmaPhase 2bplanned
  • ATI-2138ATI-2138 / ITK; JAK3 / oral covalent small-molecule inhibitor / T cell-mediated autoimmune diseases; dermatology
    lichen planusPhase 2bplannedatopic dermatitisPhase 2acompleted
  • ATI-9494ATI-9494 / ITK; TXK/RLK / oral covalent small-molecule inhibitor / Th1, Th2 and Th17-driven diseases
    undisclosed inflammatory diseasespreclinicalIND planned
  • LepzacitinibATI-1777 / JAK1; JAK3 / topical soft small-molecule inhibitor / dermatology
    atopic dermatitisPhase 2bseeking partner

Latest news13 items

All news

Aclaris Therapeutics Announces Positive Full Top Line First-in-Human Results from Phase 1a Healthy Volunteer Clinical Trial of ATI-052, a Novel Potential First-in-Class Anti-TSLP/IL-4Rα Bispecific Antibody, and Announces Lichen Planus as Lead Indication for ATI-2138, an Oral ITK/JAK3 Inhibitor

- Positive Full Results from Phase 1a Trial of Anti-TSLP/IL-4Rα Bispecific Antibody ATI-052 Exceed Aclaris’ Target Profile, Validating Potential Best-in-Class Potency Advantage and Opportunity for Extended Dosing - - Estimated Half-Life of Approximately 45 Days; Unlocks Opportunity for up to

Trial Results • Phase 1

Aclaris Therapeutics to Participate in Two February Healthcare Conferences

WAYNE, Pa., Feb. 04, 2026 (GLOBE NEWSWIRE) -- Aclaris Therapeutics, Inc. (NASDAQ: ACRS), a clinical-stage biopharmaceutical company focused on developing novel product candidates for immuno-inflammatory diseases, today announced that the Company will participate in two upcoming healthcare

Aclaris Therapeutics, Inc. • Endpoint Arena